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Mutations of BRCA1 may increase the risk of developing fallopian tube and peritoneal cancer. Men with BRCA 2 mutations are also at increased risk of breast cancer. Men with BRCA 1&2 also have a higher risk of prostate cancer. Men and women with BRCA 1&2 my also be at increased risk of pancreatic cancer. About 12 percent of women in general population will develop breast cancer but it also states that 55-65 percent with the BRCA 1 and 45 percent of BRCA 2 will develop breast cancer by age 70. About 1.4 percent of women in general population will develop ovarian cancer sometime in their lifetime but according to recent estimates 39 percent with BRCA 1 mutation and 11-17 percent of women who have the BRCA2 mutation will develop ovarian cancer by age 70. BRCA 1 &2 definitely increases your risk for breast and ovarian cancer. This test thus helps us to be ever vigilant and observant in following these people with these mutations. Eduction and early intervention can and should be discussed with a healthcare professional the most positive benefit to genetic testing. It helps to put you back in the drivers seat.
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AuthorMy name is Sue Kilburn and I am a clinical nurse breast cancer educator at the Yolanda G. Barco Oncology Institute in Meadville, Pennsylvania. Archives
March 2015
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